Tokyo, Apr 26, 2007 - (JCN Newswire) - Tokyo, Japan, Apr 25, 2007 - (JCN) - Shimadzu and Central Research laboratory discovered 9 types of protein which showed a marked variation in the numerical value on metastatic cancer. The research used central research laboratory's NOG mouse, an ultra immuno-deficient mouse in implanting human-derived pancreas and colon cancer cells.
The cells were analyzed using Shimadzu's NBS reagent, two types of stable isotope reagent which selectively indicates tryptophan - a type of amino acid in the protein - and proteome analyzed using NBS biomarker search system. As a result they were able to identify 160 types of protein which showed quantitative fluctuation in the pancreas cancer cells and 150 types in the colon cancer cells.
In a comparative analysis of the two, they detected 9 types of proteins that notably fluctuated in both cancer cells.
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Apr 26, 2007
From the Japan Corporate News Network
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Topic: Press release summary
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