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Takara Bio's RetroNect Used in Australia for Gene Therapy Clinical Trials of Multiple Myeloma
 

Tokyo, Dec 18, 2006 (JCN) - Takara Bio has entered into a license and material transfer agreement with the Peter MacCallum Cancer Centre in Melbourne, Australia to supply Takara Bio's RetroNectin for use in a phase I clinical trial of multiple myeloma (MM), which is being conducted by the group of principal investigator Professor Miles Prince. Six patients are expected to be enrolled in this phase I trial.

MM is a malignant hematological disease of the body's antibody producing cells, which causes them to grow out of control in the bone marrow, resulting in severe symptoms such as dissolution of the surrounding bone, aberration of the immune system, and renal damage.

The yearly incidence of MM is approximately 2-3 per 100,000, with an increasing incidence in the elderly. The median survival of MM patients treated with standard dose chemotherapy is only about three years.

This is the 41st clinical trial in which the RetroNectin method has been used, and is the first time the RetroNectin method has been used a clinical trial conducted outside Japan, Europe or the United States.

Currently, ex vivo gene therapy is expanding throughout the world as an effective treatment method for several incurable diseases. As a result, the RetroNectin method is becoming recognized as an essential and standard technology for ex vivo gene therapy.

By Chris Lui Staff Writer

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